"How do I know if my gut or liver is involved in my Allergies?"
- sara6297
- Mar 28
- 2 min read

Someone emailed me this after a recent talk, where I shared how chronic allergies and histamine symptoms often stem from deeper issues in the gut and liver. It’s a brilliant question—because it’s rarely talked about in conventional allergy care.
If you’re reacting to everything and antihistamines are no longer cutting it, there’s a strong chance your gut or liver (or both) are involved.
Why Your Gut Matters
Over 70% of your immune system lives in the gut. If your gut lining is inflamed or your microbiome is out of balance, your immune system becomes over-sensitive, reacting to harmless things like pollen, food, or smells.
Your gut is also responsible for breaking down histamine. If the enzyme that does this (DAO) is low—or if the gut lining is damaged—histamine builds up in your system.
Signs your gut may be contributing to allergies:
Bloating, gas, or irregular bowel movements
Reacting to fermented foods, wine, or cheese
Brain fog, mood swings, or fatigue after meals
Skin issues like itching, hives, or rashes
Ongoing food sensitivities or intolerances
How the Liver Gets Involved
Your liver plays a key role in clearing histamine, toxins, and inflammatory chemicals. If it’s sluggish or overwhelmed, histamine clearance slows down—and symptoms worsen.
Clues your liver might need support:
Sensitivity to alcohol, caffeine, or chemical smells
Waking regularly between 2–4am
PMS, skin issues, or feeling puffy and foggy
Fatigue despite eating well
Here’s the thing:
Long-term antihistamine use might give temporary relief, but it can actually make things worse. These medications can impair digestion, dehydrate the gut lining, disrupt the microbiome, and burden the liver—worsening the root issues behind histamine overload.
That’s why instead of chasing symptoms, I recommend targeted functional testing—we can look at gut bacteria, inflammation markers, histamine load, liver function, and more. This gives us a clear picture of what your body actually needs to heal.
If you’re stuck in a cycle of allergy meds, brain fog, and reactions, it’s time to look deeper.
Book a free discovery call if you want to explore what’s really going on in your body. There’s a better way—and it starts with listening to what your symptoms are trying to tell you.